Description
Supplied as a lyophilized powder that must be reconstituted with bacteriostatic water prior to research use.
📌 What Is Melanotan 1?
Melanotan 1, also known as Afamelanotide, is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH). It enhances skin pigmentation and provides protection against UV exposure by increasing melanin production. Unlike Melanotan 2, it has minimal effects on libido and is primarily studied for photoprotective benefits.
🌞 Skin Pigmentation & Tanning
-Encourages a more even, natural-looking tan with reduced reliance on UV exposure
🛡️ UV Protection
-Increases melanin levels to help reduce sunburn risk and UV-related skin damage
🩹 Skin Disorder Treatment
-FDA- and EMA-approved (as Afamelanotide / Scenesse®) for erythropoietic protoporphyria (EPP), a rare sunlight sensitivity disorder
⚡ Cosmetic Research
-Investigated for reducing sun damage and promoting more uniform skin tone
⚙️ Mechanism of Action
-Binds to melanocortin-1 receptors (MC1R) in skin cells
-Stimulates melanin synthesis, the pigment responsible for skin and hair coloration
-Provides both cosmetic pigmentation effects and medical photoprotection
📈 Key Benefits
✅ Deeper, more uniform skin tone
✅ Reduced susceptibility to sunburn and UV damage
✅ FDA/EMA approval for EPP treatment (Scenesse® implant)
✅ Lower tendency for freckle or mole darkening compared to Melanotan 2
⚠ Note: Although Melanotan 1 (Afamelanotide) is approved for specific medical indications, its use is for research purpose only. No human consumption.


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